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Article

Behçet's spectrum disorders: genetic and immunological insights into an emerging disease concept.

World journal of pediatrics : WJP - 1 Jun 2026

Zhang Hui-Nan, Gao Si-Hao, Wang Wei, Huang Guo-Ying, Song Hong-Mei

Abstract excerpt

BACKGROUND: Behçet's spectrum disorders (BSD) describe a conceptual framework encompassing inflammatory conditions with overlapping clinical and genetic features with Behçet's disease. First introduced in 2020, the BSD concept was proposed to contextualize BD-like inflammation in pediatric and early-onset cases by linking clinical phenotypes to shared immune pathways and supporting earlier prioritization of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42337193
DOI: 10.1007/s12519-026-01035-4

Genes

ELF4
NFKB1
RELA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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