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Article

TNAP as a New Player in Chronic Inflammatory Conditions and Metabolism.

International journal of molecular sciences - 18 Jan 2021

Graser Stephanie, Liedtke Daniel, Jakob Franz

Abstract excerpt

This review summarizes important information on the ectoenzyme tissue-nonspecific alkaline phosphatase (TNAP) and gives a brief insight into the symptoms, diagnostics, and treatment of the rare disease Hypophosphatasia (HPP), which is resulting from mutations in the TNAP encoding ALPL gene. We emphasize the role of TNAP beyond its well-known contribution to mineralization processes. Therefore, above all, the...

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Identifiers

PMID: 33477631
DOI: 10.3390/ijms22020919
PMCID: PMC7831495

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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