Article
Tissue-Nonspecific Alkaline Phosphatase-A Gatekeeper of Physiological Conditions in Health and a Modulator of Biological Environments in Disease.
Biomolecules - 8 Dec 2020
Liedtke Daniel, Hofmann Christine, Jakob Franz, Klopocki Eva, Graser Stephanie
Abstract excerpt
Tissue-nonspecific alkaline phosphatase (TNAP) is a ubiquitously expressed enzyme that is best known for its role during mineralization processes in bones and skeleton. The enzyme metabolizes phosphate compounds like inorganic pyrophosphate and pyridoxal-5'-phosphate to provide, among others, inorganic phosphate for the mineralization and transportable vitamin B6 molecules. Patients with inherited loss of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.