Article
Gliomatosis Cerebri Growth Pattern: Association of Differential First-Line Treatment with Overall Survival in WHO Grade II and III Gliomas.
Oncology - 1 Jan 2021
Divé Iris, Steidl Eike, Wagner Marlies, Filipski Katharina, Burger Michael C, Franz Kea, Harter Patrick N, Bähr Oliver, Fokas Emmanouil, Herrlinger Ulrich, Steinbach Joachim P
Abstract excerpt
INTRODUCTION: Gliomatosis cerebri (GC) is defined by diffuse, widespread glial tumor growth affecting three or more cerebral lobes. Previous studies in gliomas found no distinct histological or molecular GC subtype, yet the presence of GC is associated with worse median overall survival (OS). Here, we explored whether differing therapeutic strategies in first-line treatment could account for this. METHODS: From...
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