Article
Simple and efficient isolation of cordycepin from culture broth of a Cordyceps militaris mutant.
Journal of bioscience and bioengineering - 1 Dec 2015
Masuda Mina, Hatashita Masanori, Fujihara Shinya, Suzuki Yu, Sakurai Akihiko
Abstract excerpt
Isolation of cordycepin from the culture broth of Cordyceps militaris mutant was investigated. Based on the solubility curve, three crystallizing processes, temperature shift (process I), pH shift (process II), and pH shift followed by temperature shift (process III) were carried out. Process III was the most promising method regarding both purity and yield.
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