Article
Inositol pyrophosphates promote the interaction of SPX domains with the coiled-coil motif of PHR transcription factors to regulate plant phosphate homeostasis.
Nature communications - 15 Jan 2021
Ried Martina K, Wild Rebekka, Zhu Jinsheng, Pipercevic Joka, Sturm Kristina, Broger Larissa, Harmel Robert K, Abriata Luciano A, Hothorn Ludwig A, Fiedler Dorothea, Hiller Sebastian, Hothorn Michael
Abstract excerpt
Phosphorus is an essential nutrient taken up by organisms in the form of inorganic phosphate (Pi). Eukaryotes have evolved sophisticated Pi sensing and signaling cascades, enabling them to stably maintain cellular Pi concentrations. Pi homeostasis is regulated by inositol pyrophosphate signaling molecules (PP-InsPs), which are sensed by SPX domain-containing proteins. In plants, PP-InsP-bound SPX receptors...
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