Article
Extracellular protease profile of Acanthamoeba after prolonged axenic culture and after interaction with MDCK cells.
Parasitology research - 1 Feb 2020
Cirelli Cecília, Mesquita Elaine Isabela Soares, Chagas Isabela Aurora Rodrigues, Furst Cinthia, Possamai Cynara Oliveira, Abrahão Jonatas Santos, Dos Santos Silva Ludmila Karen, Grossi Marina Felipe, Tagliati Carlos Alberto, Costa Adriana Oliveira
Abstract excerpt
Free-living amoebae of the genus Acanthamoeba are causative agents of Acanthamoeba keratitis and amoebic encephalitis in humans, both of which are serious infections. The ability to produce proteases is one of the factors involved in the pathogenesis of Acanthamoeba infections. The aim of this study was to evaluate the secreted proteases of six Acanthamoeba strains from distinct genotypes (T1, T2, T4 and T11)...
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