Article
Novel genetic characteristics of multifocal micronodular pneumocyte hyperplasia (MMPH): a case report with frequent BRAF mutations analyzed by next-generation sequencing supporting benign behaviors of MMPH.
Virchows Archiv : an international journal of pathology - 1 Sept 2021
Inoue Chihiro, Saito Ryoko, Kishikawa Satsuki, Hayashi Takuo, Kumasaka Toshio, Yamada Takehiro, Oishi Hisashi, Yamazaki Yuto, Fujishima Fumiyoshi, Watanabe Mika, Sasano Hironobu
Abstract excerpt
A woman in her 30s, who was clinically diagnosed with tuberous sclerosis complex, underwent lung transplantation due to lymphangioleiomyomatosis with concomitant multifocal micronodular pneumocyte hyperplasia (MMPH). Histologically, MMPH lesions demonstrated variety in histology; some showed homogenous cells with mild nuclear atypia and elastic fibers proliferation, and the others showed enlarged nuclei without...
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