Primary Immune Regulatory Disorders and Targeted Therapies

doi:10.4274/tjh.galenos.2021.2020.0724

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Article

Primary Immune Regulatory Disorders and Targeted Therapies

Turkish journal of haematology : official journal of Turkish Society of Haematology - 25 Feb 2021

Kolukısa Burcu, Barış Safa

Abstract excerpt

Primary immune regulatory disorders (PIRDs) are a group of diseases belonging to inborn errors of immunity. They usually exhibit lymphoproliferation, autoimmunities, and malignancies, with less susceptibility to recurrent infections. Unlike classical primary immune deficiencies, in autoimmune manifestations, such as cytopenias, enteropathy can be the first symptom of diseases, and they are typically resistant to...

Topics

Alleles
Animals
Autoimmunity
Biomarkers
Cytophagocytosis
Cytotoxicity, Immunologic
Gain of Function Mutation
Gene Expression Regulation
Genetic Predisposition to Disease
Genetic Therapy
Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Immunomodulation

Lymphocytes

Molecular Targeted Therapy

Organ Specificity

Phenotype

Primary Immunodeficiency Diseases

Source

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Identifiers

PMID: 33442967
DOI: 10.4274/tjh.galenos.2021.2020.0724
PMCID: PMC7927447

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