Article
Primary immune regulatory disorders: a growing universe of immune dysregulation.
Current opinion in allergy and clinical immunology - 1 Dec 2020
Chan Alice Y, Torgerson Troy R
Abstract excerpt
PURPOSE OF REVIEW: Primary immune regulatory disorders (PIRD) are a growing subset of diseases referred to as inborn errors of immunity. Unlike classical primary immune deficiency disorders that typically present with severe, recurrent, or unusual infections, the clinical manifestations of PIRD are dominated by immune-mediated diseases (autoimmunity, autoinflammation/hyperinflammation, lymphoproliferation,...
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