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Variability of an Early Developmental Cell Population Underlies Stochastic Laterality Defects.

Cell reports - 12 Jan 2021

Moreno-Ayala Roberto, Olivares-Chauvet Pedro, Schäfer Ronny, Junker Jan Philipp

Abstract excerpt

Embryonic development seemingly proceeds with almost perfect precision. However, it is largely unknown how much underlying microscopic variability is compatible with normal development. Here, we quantify embryo-to-embryo variability in vertebrate development by studying cell number variation in the zebrafish endoderm. We notice that the size of a sub-population of the endoderm, the dorsal forerunner cells (DFCs,...

Topics

Animals
Embryo, Nonmammalian
Phenotype
Zebrafish
Zebrafish Proteins

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 33440143
DOI: 10.1016/j.celrep.2020.108606
PMCID: PMC7809618

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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