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Chemotaxis and swarming in differentiated HL-60 neutrophil-like cells

12 Jan 2021

Abstract excerpt

The human leukemia cell line (HL-60) is an alternative to primary neutrophils in research studies. However, because HL-60 cells proliferate in an incompletely differentiated state, they must undergo differentiation before they acquire the functional properties of neutrophils. Here we provide evidence of swarming and chemotaxis in differentiated HL-60 neutrophil-like cells (dHL-60) using precise microfluidic...

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PMID: 33436661
DOI: 10.1038/s41598-020-78854-6

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