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Phenethyl isothiocyanate reduces breast cancer stem cell-like properties by epigenetic reactivation of CDH1

19 Nov 2020

Abstract excerpt

Breast cancer is the most frequently diagnosed malignancy and leading cause of cancer-related deaths among women worldwide. Tumor recurrence, or metastasis, is caused by cancer stem cells and has a dismal prognosis for breast cancer patients. Thus, targeting breast cancer stem cells (BCSCs) for eradication is a potential method to improve clinical outcomes. Phenethyl isothiocyanate (PEITC) is a novel epigenetic...

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PMID: 33416137
DOI: 10.3892/or.2020.7860

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