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Article

Association of protein tyrosine phosphatase 1B gene polymorphism with the effects of weight reduction therapy on bodyweight and glycolipid profiles in obese patients.

Journal of diabetes investigation - 1 Aug 2021

Yamakage Hajime, Konishi Yousuke, Muranaka Kazuya, Hotta Kikuko, Miyamoto Yoshihiro, Morisaki Hiroko, Morisaki Takayuki, Satoh-Asahara Noriko

Abstract excerpt

AIMS/INTRODUCTION: Weight reduction therapy is the primary treatment to prevent complications of obesity, such as lifestyle diseases and cardiovascular disease; however, to date, useful methods and genetic factors for predicting the outcomes of weight reduction therapy in obese patients have not been established. Protein tyrosine phosphatase 1B (PTP1B), a negative regulator for insulin and leptin signaling,...

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Share to Body Mass Index
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 33400373
DOI: 10.1111/jdi.13492
PMCID: PMC8354504

Genes

PTPN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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