Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Altered Gene Expression along the Glycolysis–Cholesterol Synthesis Axis Is Associated with Outcome in Pancreatic Cancer

3 Sept 2019

Abstract excerpt

Abstract Purpose: Identification of clinically actionable molecular subtypes of pancreatic ductal adenocarcinoma (PDAC) is key to improving patient outcome. Intertumoral metabolic heterogeneity contributes to cancer survival and the balance between distinct metabolic pathways may influence PDAC outcome. We hypothesized that PDAC can be stratified into prognostic metabolic subgroups based on alterations in the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer, Lipids, and Metabolism
Share to Ferroptosis and cancer prognosis
Share to Pancreatic and Hepatic Oncology Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31481506
DOI: 10.1158/1078-0432.ccr-19-1543

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Altered Gene Expression along the Glycolysis–Cholesterol Synthesis Axis Is Associated with Outcome in Pancreatic CancerPMID 31481506Read ↗

Molecular and Metabolic Subtypes Correspondence for Pancreatic Ductal Adenocarcinoma ClassificationSemantic proximity Read ↗

Glycolysis-Based Genes Associated with the Clinical Outcome of Pancreatic Ductal Adenocarcinoma Identified by The Cancer Genome Atlas Data AnalysisSemantic proximity Read ↗

Clinically impactful metabolic subtypes of pancreatic ductal adenocarcinoma (PDAC)Semantic proximity Read ↗

Glycometabolic rearrangements–aerobic glycolysis in pancreatic ductal adenocarcinoma (PDAC): roles, regulatory networks, and therapeutic potentialSemantic proximity Read ↗

Glycolysis-stratified coordination of fatty acid and glutamine metabolism in pancreatic ductal adenocarcinomaSemantic proximity Read ↗

Pancreatic cancer tumor organoids exhibit subtype-specific differences in metabolic profilesSemantic proximity Read ↗

Exploring the metabolic landscape of pancreatic ductal adenocarcinoma cells using genome-scale metabolic modelingSemantic proximity Read ↗

Plasma Metabolome Profiling Identifies Metabolic Subtypes of Pancreatic Ductal AdenocarcinomaSemantic proximity Read ↗

Glucose metabolic phenotype of pancreatic cancer.Semantic proximity Read ↗

Integrating metabolic profiling of pancreatic juice with transcriptomic analysis of pancreatic cancer tissue identifies distinct clinical subgroupsSemantic proximity Read ↗

Metabolomic profiling of pancreatic adenocarcinoma reveals key features driving clinical outcome and drug resistance.Semantic proximity Read ↗

Glycolysis-Related Gene Expression Profiling Screen for Prognostic Risk Signature of Pancreatic Ductal AdenocarcinomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.