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Article

Genotype-Specific Differences in Circulating Tumor DNA Levels in Advanced NSCLC.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Apr 2021

Lam Vincent K, Zhang Jianjun, Wu Carol C, Tran Hai T, Li Lerong, Diao Lixia, Wang Jing, Rinsurongkawong Waree, Raymond Victoria M, Lanman Richard B, Lewis Jeff, Roarty Emily B, Roth Jack, Swisher Stephen, Lee J Jack, Gibbons Don L, Papadimitrakopoulou Vassiliki A, Heymach John V

Abstract excerpt

INTRODUCTION: Plasma-based circulating tumor DNA (ctDNA) is an established biomarker for molecular profiling with emerging applications in disease monitoring in multiple tumor types, including, NSCLC. However, determinants of ctDNA shedding and correlation with tumor burden are incompletely understood, particularly in advanced-stage disease. METHODS: We retrospectively analyzed ctDNA-based and tissue-based...

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Identifiers

PMID: 33388476
DOI: 10.1016/j.jtho.2020.12.011
PMCID: PMC8012216

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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