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Definition of erythroid cell‐positive blood transcriptome phenotypes associated with severe respiratory syncytial virus infection

1 Dec 2020

Abstract excerpt

Biomarkers to assess the risk of developing severe respiratory syncytial virus (RSV) infection are needed. We conducted a meta-analysis of 490 unique profiles from six public RSV blood transcriptome datasets. A repertoire of 382 well-characterized transcriptional modules was used to define dominant host responses to RSV infection. The consolidated RSV cohort was stratified according to four traits: "interferon...

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PMID: 33377660
DOI: 10.1002/ctm2.244

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