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Article

Gene signature of children with severe respiratory syncytial virus infection.

Pediatric research - 1 May 2021

Dapat Clyde, Kumaki Satoru, Sakurai Hiroki, Nishimura Hidekazu, Labayo Hannah Karen Mina, Okamoto Michiko, Saito Mayuko, Oshitani Hitoshi

Abstract excerpt

BACKGROUND: The limited treatment options for children with severe respiratory syncytial virus (RSV) infection highlights the need for a comprehensive understanding of the host cellular response during infection. We aimed to identify host genes that are associated with severe RSV disease and to identify drugs that can be repurposed for the treatment of severe RSV infection. METHODS: We examined clinical data and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33510411
DOI: 10.1038/s41390-020-01347-9
PMCID: PMC8249238

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