Article
MOLECULAR GENETIC ABNORMALITIES IN THE GENOME OF PATIENTS WITH Ph-NEGATIVE MYELOPROLIFERATIVE NEOPLASIA AFFECTED BY IONIZING RADIATION AS A RESULT OF THE CHORNOBYL NUCLEAR ACCIDENT.
Problemy radiatsiinoi medytsyny ta radiobiolohii - 1 Dec 2020
Poluben L O, Neumerzhytska L V, Klymenko S V, Fraenkel P, Balk C, Shumeiko O O
Abstract excerpt
OBJECTIVE: to determine the frequency of major somatic mutations in the JAK2, MPL and CALR genes in the genomeof patients with Ph-negative myeloproliferative neoplasms that occur in individuals who have been exposed to ionizing radiation as a result of the Chornobyl accident. MATERIALS AND METHODS: Molecular genetic analysis of genomic DNA samples isolated from blood was performed in90 patients with Ph-negative...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.