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Article

Application of a Sanger-Based External Quality Assurance Strategy for the Transition of HIV-1 Drug Resistance Assays to Next Generation Sequencing.

Viruses - 17 Dec 2020

Jennings Cheryl, Parkin Neil T, Zaccaro Daniel J, Capina Rupert, Sandstrom Paul, Ji Hezhao, Brambilla Donald J, Bremer James W

Abstract excerpt

The National Institute of Allergy and Infectious Diseases (NIAID) Virology Quality Assurance (VQA) established a robust proficiency testing program for Sanger sequencing (SS)-based HIV-1 drug resistance (HIVDR) testing in 2001. While many of the lessons learned during the development of such programs may also apply to next generation sequencing (NGS)-based HIVDR assays, challenges remain for the ongoing...

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Identifiers

PMID: 33348705
DOI: 10.3390/v12121456
PMCID: PMC7766986

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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