Article
External Quality Assessment Program for Next-Generation Sequencing-Based HIV Drug Resistance Testing: Logistical Considerations.
Viruses - 18 May 2020
Ji Hezhao, Parkin Neil, Gao Feng, Denny Thomas, Jennings Cheryl, Sandstrom Paul, Kantor Rami
Abstract excerpt
Next-generation sequencing (NGS) is likely to become the new standard method for HIV drug resistance (HIVDR) genotyping. Despite the significant advances in the development of wet-lab protocols and bioinformatic data processing pipelines, one often-missing critical component of an NGS HIVDR assay for clinical use is external quality assessment (EQA). EQA is essential for ensuring assay consistency and laboratory...
Topics
- Congresses as Topic
- Diagnostic Tests, Routine
- Drug Resistance, Viral
- Genotype
- HIV Infections
- HIV-1
- High-Throughput Nucleotide Sequencing
- Quality Assurance, Health Care
- Sequence Analysis, RNA