Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

β2 Integrins—Multi-Functional Leukocyte Receptors in Health and Disease

19 Feb 2020

Abstract excerpt

β2 integrins are heterodimeric surface receptors composed of a variable α (CD11a-CD11d) and a constant β (CD18) subunit and are specifically expressed by leukocytes. The α subunit defines the individual functional properties of the corresponding β2 integrin, but all β2 integrins show functional overlap. They mediate adhesion to other cells and to components of the extracellular matrix (ECM), orchestrate uptake of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blood disorders and treatments
Share to Cell Adhesion Molecules Research
Share to Immunotherapy and Immune Responses

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32092981
DOI: 10.3390/ijms21041402

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

β2 Integrins—Multi-Functional Leukocyte Receptors in Health and DiseasePMID 32092981Read ↗

Integrins in Health and Disease—Suitable Targets for Treatment?Semantic proximity Read ↗

Biology and structure of leukocyte β2 integrins and their role in inflammationSemantic proximity Read ↗

Leukocyte adhesion deficiency syndromes: adhesion and tethering defects involving beta 2 integrins and selectin ligands.Semantic proximity Read ↗

Beta2-Integrins and Interacting Proteins in Leukocyte Trafficking, Immune Suppression, and Immunodeficiency DiseaseSemantic proximity Read ↗

The Leukocyte IntegrinsSemantic proximity Read ↗

LFA-1 in T Cell Migration and DifferentiationSemantic proximity Read ↗

β1- and β2-integrins: central players in regulating vascular permeability and leukocyte recruitment during acute inflammationSemantic proximity Read ↗

β2 Integrin Signaling Cascade in Neutrophils: More Than a Single FunctionSemantic proximity Read ↗

The Integrin Receptors: From Discovery to Structure to MedicinesSemantic proximity Read ↗

Integrin αDβ2 (CD11d/CD18) Is Expressed by Human Circulating and Tissue Myeloid Leukocytes and Mediates Inflammatory SignalingSemantic proximity Read ↗

Regulation and functions of integrin α2 in cell adhesion and diseaseSemantic proximity Read ↗

Targeting leukocyte integrins in human diseasesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.