Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Chromosome 20 loss is characteristic of breast implant-associated anaplastic large cell lymphoma.

Blood - 17 Dec 2020

Los-de Vries G Tjitske, de Boer Mintsje, van Dijk Erik, Stathi Phylicia, Hijmering Nathalie J, Roemer Margaretha G M, Mendeville Matias, Miedema Daniel M, de Boer Jan Paul, Rakhorst Hinne A, van Leeuwen Flora E, van der Hulst René R W J, Ylstra Bauke, de Jong Daphne

Abstract excerpt

Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is a very rare type of T-cell lymphoma that is uniquely caused by a single environmental stimulus. Here, we present a comprehensive genetic analysis of a relatively large series of BIA-ALCL (n = 29), for which genome-wide chromosomal copy number aberrations (CNAs) and mutational profiles for a subset (n = 7) were determined. For comparison, CNAs...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Breast Cancer Treatment Studies
Share to Breast Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cancer and Skin Lesions

Share to Chromosome Deletion

Share to Chromosomes, Human, Pair 20

Share to Lymphoma, Large-Cell, Anaplastic

Share to Mutation

Share to Neoplasm Proteins

Source

Identifiers

PMID: 33331925
DOI: 10.1182/blood.2020005372

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Chromosome 20 loss is characteristic of breast implant-associated anaplastic large cell lymphoma.PMID 33331925Read ↗

Genetics of Breast Implant-Associated Anaplastic Large Cell Lymphoma (BIA-ALCL).Semantic proximity Read ↗

BIA-ALCL and BIA-SCC: Updates on Clinical Features and Genetic Mutations for Latest Recommendations.Semantic proximity Read ↗

Cell of Origin and Immunologic Events in the Pathogenesis of Breast Implant–Associated Anaplastic Large-Cell LymphomaSemantic proximity Read ↗

Next generation sequencing of breast implant-associated anaplastic large cell lymphomas reveals a novel STAT3-JAK2 fusion among other activating genetic alterations within the JAK-STAT pathway.Semantic proximity Read ↗

Frequent activating STAT3 mutations and novel recurrent genomic abnormalities detected in breast implant-associated anaplastic large cell lymphomaSemantic proximity Read ↗

ALCL by any other name: the many facets of anaplastic large cell lymphoma.Semantic proximity Read ↗

Cellular and Molecular Mechanisms of Breast Implant-Associated Anaplastic Large Cell Lymphoma.Semantic proximity Read ↗

Gene alterations in epigenetic modifiers and JAK-STAT signaling are frequent in breast implant-associated ALCL.Semantic proximity Read ↗

Evaluation of Breast Implant-Associated Anaplastic Large Cell Lymphoma With Whole Exome and Genome Sequencing.Semantic proximity Read ↗

Fibrin associated large B-cell lymphoma accidentally identified in a breast implant capsule: a molecular report of a rare entity.Semantic proximity Read ↗

Establishment and characterization of a novel breast implant-associated anaplastic large cell lymphoma cell line and PDX model (BIA-XR1) with a unique KRAS mutation.Semantic proximity Read ↗

A Case Report of Breast Implant-Associated Anaplastic Large-Cell Lymphoma in a PALB2 Mutation-Positive Woman.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.