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Article

Establishment and characterization of a novel breast implant-associated anaplastic large cell lymphoma cell line and PDX model (BIA-XR1) with a unique KRAS mutation.

Current research in translational medicine - 1 Jan 2023

Xagoraris Ioanna, Stathopoulou Konstantina, Aulerio Roberta D', He Minghui, Ketscher Anett, Jatta Kenbugul, de Flon Felix Haglund, Barbany Gisela, Rosenquist Richard, Westerberg Lisa S, Rassidakis George Z

Abstract excerpt

Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is an uncommon T-cell lymphoma type with distinct clinical, molecular and genetic features. Establishment of BIA-ALCL cell lines and patient-derived xenograft (PDX) models are essential experimental tools to investigate the molecular pathogenesis of the disease. We characterized a novel BIA-ALCL cell line and PDX model, named BIA-XR1, derived...

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Share to Breast Neoplasms
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Disease Models, Animal

Share to Lymphoma, Large-Cell, Anaplastic

Share to Proto-Oncogene Proteins p21(ras)

Share to STAT3 Transcription Factor

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Source

Identifiers

PMID: 37364351
DOI: 10.1016/j.retram.2023.103401

Genes

KRAS
STAT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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