Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

DEAD-box RNA helicase protein DDX21 as a prognosis marker for early stage colorectal cancer with microsatellite instability

16 Dec 2020

Abstract excerpt

DEAD-box RNA helicase DDX21 (also named nucleolar RNA helicase 2) is a nuclear autoantigen with undefined roles in cancer. To explore possible roles of autoimmune recognition in cancer immunity, we examined DDX21 protein expression in colorectal cancer tissue and its association with patient clinical outcomes. Unbiased deep proteomic profiling of two independent colorectal cancer cohorts using mass spectrometry...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic factors in colorectal cancer
Share to RNA modifications and cancer
Share to RNA Research and Splicing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33328538
DOI: 10.1038/s41598-020-79049-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

DEAD-box RNA helicase protein DDX21 as a prognosis marker for early stage colorectal cancer with microsatellite instabilityPMID 33328538Read ↗

Genomic analyses identify significant biological processes in DDX21-mediated colorectal cancer cellsSemantic proximity Read ↗

Pan-cancer analysis reveals DDX21 as a potential biomarker for the prognosis of multiple tumor typesSemantic proximity Read ↗

Clinical proteomics identified ATP-dependent RNA helicase DDX39 as a novel biomarker to predict poor prognosis of patients with gastrointestinal stromal tumorSemantic proximity Read ↗

DEAD-box helicase 27 promotes colorectal cancer growth and metastasis and predicts poor survival in CRC patientsSemantic proximity Read ↗

DDX10 Promotes the Proliferation and Metastasis of Colorectal Cancer Cells via Splicing RPL35Semantic proximity Read ↗

A Comprehensive Integrated Analysis of DDX3X Expression, Prognostic Value and Potential Implications for Pan-Cancer ImmunitySemantic proximity Read ↗

Glutathione peroxidase 2: A key factor in the development of microsatellite instability in colon cancerSemantic proximity Read ↗

The RNA helicase DDX21 cooperates with ETS1 and FLI1 in cell cycle, immune evasion, and snoRNA processing in activated B-cell-like diffuse large B-cell lymphoma cellsSemantic proximity Read ↗

The RNA-binding protein DDX39B promotes colorectal adenocarcinoma progression by stabilizing DCLK1Semantic proximity Read ↗

An E2F1/DDX11/EZH2 Positive Feedback Loop Promotes Cell Proliferation in Hepatocellular CarcinomaSemantic proximity Read ↗

DDX3 acts as a tumor suppressor in colorectal cancer as loss of DDX3 in advanced cancer promotes tumor progression by activating the MAPK pathwaySemantic proximity Read ↗

Ubiquitination-related regulator UBTD1 closely associated with Immune Escape and suppressed cells ferroptosis in Colorectal CarcinogenesisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.