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Article

Co-expression of cancer driver genes: IDH-wildtype glioblastoma-derived tumorspheres.

Journal of translational medicine - 14 Dec 2020

Yoon Seon-Jin, Son Hye Young, Shim Jin-Kyoung, Moon Ju Hyung, Kim Eui-Hyun, Chang Jong Hee, Teo Wan Yee, Kim Se Hoon, Park Sahng Wook, Huh Yong-Min, Kang Seok-Gu

Abstract excerpt

BACKGROUND: Driver genes of GBM may be crucial for the onset of isocitrate dehydrogenase (IDH)-wildtype (WT) glioblastoma (GBM). However, it is still unknown whether the genes are expressed in the identical cluster of cells. Here, we have examined the gene expression patterns of GBM tissues and patient-derived tumorspheres (TSs) and aimed to find a progression-related gene. METHODS: We retrospectively collected...

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Identifiers

PMID: 33317554
DOI: 10.1186/s12967-020-02647-8
PMCID: PMC7734785

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