Article
Genetic variation in the TLL1 gene is not associated with fibrosis in patients with metabolic associated fatty liver disease.
PloS one - 1 Jan 2020
Bayoumi Ali, Jalil Ismail, Metwally Mayada, Adams Leon A, Aller Rocio, García-Monzón Carmelo, Arias-Loste María Teresa, Miele Luca, Petta Salvatore, Craxì Antonio, Gallego-Durán Rocio, Fischer Janett, Berg Thomas, Qiao Liang, Liddle Christopher, Bugianesi Elisabetta, Romero-Gomez Manuel, George Jacob, Eslam Mohammed
Abstract excerpt
Metabolic associated fatty liver disease (MAFLD) is the most prevalent liver disease in Western nations, with high heritability. A recent study of Japanese patients with the disease suggested that TLL1 rs17047200 is associated with fibrosis; whether a similar association is observed in Caucasian patients with MAFLD is unknown. We investigated the association of the TLL1 rs17047200 polymorphism with liver fibrosis...
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