Article
Genomic analysis of the meningococcal ST-4821 complex-Western clade, potential sexual transmission and predicted antibiotic susceptibility and vaccine coverage.
PloS one - 1 Jan 2020
Lucidarme Jay, Zhu Bingqing, Xu Li, Bai Xilian, Gao Yuan, González-López Juan José, Mulhall Robert, Scott Kevin J, Smith Andrew, Stefanelli Paola, Stenmark Bianca, Torpiano Paul, Tzanakaki Georgina, Borrow Ray, Shao Zhujun
Abstract excerpt
INTRODUCTION: The ST-4821 complex (cc4821) is a leading cause of serogroup C and serogroup B invasive meningococcal disease in China where diverse strains in two phylogenetic groups (groups 1 and 2) have acquired fluoroquinolone resistance. cc4821 was recently prevalent among carriage isolates in men who have sex with men in New York City (USA). Genome-level population studies have thus far been limited to...
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