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Article

Evolution of Sequence Type 4821 Clonal Complex Meningococcal Strains in China from Prequinolone to Quinolone Era, 1972-2013.

Emerging infectious diseases - 1 Apr 2018

Guo Qinglan, Mustapha Mustapha M, Chen Mingliang, Qu Di, Zhang Xi, Chen Min, Doi Yohei, Wang Minggui, Harrison Lee H

Abstract excerpt

The expansion of hypervirulent sequence type 4821 clonal complex (CC4821) lineage Neisseria meningitidis bacteria has led to a shift in meningococcal disease epidemiology in China, from serogroup A (MenA) to MenC. Knowledge of the evolution and genetic origin of the emergent MenC strains is limited. In this study, we subjected 76 CC4821 isolates collected across China during 1972-1977 and 2005-2013 to...

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Identifiers

PMID: 29553310
DOI: 10.3201/eid2404.171744
PMCID: PMC5875256

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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