Article
Identification and characterization of two consistent osteoarthritis subtypes by transcriptome and clinical data integration.
Rheumatology (Oxford, England) - 2 Mar 2021
Coutinho de Almeida Rodrigo, Mahfouz Ahmed, Mei Hailiang, Houtman Evelyn, den Hollander Wouter, Soul Jamie, Suchiman Eka, Lakenberg Nico, Meessen Jennifer, Huetink Kasper, Nelissen Rob G H H, Ramos Yolande F M, Reinders Marcel, Meulenbelt Ingrid
Abstract excerpt
OBJECTIVE: To identify OA subtypes based on cartilage transcriptomic data in cartilage tissue and characterize their underlying pathophysiological processes and/or clinically relevant characteristics. METHODS: This study includes n = 66 primary OA patients (41 knees and 25 hips), who underwent a joint replacement surgery, from which macroscopically unaffected (preserved, n = 56) and lesioned (n = 45) OA articular...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.