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Article

Quantitative Susceptibility Mapping of the Hippocampal Fimbria in Alzheimer's Disease

9 Dec 2020

Abstract excerpt

Background The fimbria is a small white matter bundle that connects the hippocampus to the rest of the brain. Damage to the hippocampal gray matter is established in Alzheimer's disease (AD), but the hippocampal fimbrial status in the pathogenesis of AD is unclear. AD‐related demyelination and iron deposition alter the diamagnetic and paramagnetic composition of tissues, which can be measured by quantitative...

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PMID: 33295658
DOI: 10.1002/jmri.27464

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