Article
Women with polycystic ovary syndrome and other causes of infertility have a higher prevalence of GSTT1 deletion.
Reproductive biomedicine online - 1 Nov 2020
Alves Maria Manuel Casteleiro, Almeida Micaela, Oliani António Hélio, Breitenfeld Luiza, Ramalhinho Ana Cristina
Abstract excerpt
RESEARCH QUESTION: Is GSTM1 and GSTT1 deletion associated with the development of polycystic ovary syndrome (PCOS)? DESIGN: A case-control study was designed to investigate the association between GSTM1 and GSTT1 gene polymorphisms with PCOS. Blood samples from 201 women diagnosed with infertility were taken, of which 69 women were diagnosed with PCOS. Genomic DNA was extracted, and genotyping analyses were...
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