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Pontin arginine methylation by CARM1 is crucial for epigenetic regulation of autophagy

8 Dec 2020

Abstract excerpt

Autophagy is a catabolic process through which cytoplasmic components are degraded and recycled in response to various stresses including starvation. Recently, transcriptional and epigenetic regulations of autophagy have emerged as essential mechanisms for maintaining homeostasis. Here, we identify that coactivator-associated arginine methyltransferase 1 (CARM1) methylates Pontin chromatin-remodeling factor under...

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Share to Autophagy in Disease and Therapy
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PMID: 33293536
DOI: 10.1038/s41467-020-20080-9

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