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Identification and validation of endogenous control miRNAs in plasma samples for normalization of qPCR data for Alzheimer’s disease

1 Dec 2020

Abstract excerpt

BACKGROUND: MicroRNAs (miRNAs) are noncoding RNAs that are highly relevant as disease biomarkers. Several studies that explored the role of miRNAs in Alzheimer's disease (AD) demonstrated their usefulness in clinical identification. Nevertheless, miRNAs that may act as endogenous controls (ECs) have not yet been established. The identification of ECs would contribute to the standardization of these biomarkers in...

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PMID: 33278902
DOI: 10.1186/s13195-020-00735-x

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