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Article

Age-related DNA methylation changes are sex-specific: a comprehensive assessment

3 Dec 2020

Abstract excerpt

genes and showed sex-specific deviations of their methylation patterns in models of decelerated (centenarians) and accelerated (Down syndrome) aging. While we did not find sex differences in the age-associated increase in epimutations and entropy, we showed that the number of probes having an age-related increase in methylation variability is 15 times higher in males compared to females. Our results can offer new...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33276343
DOI: 10.18632/aging.202251

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