Article
Intestinal phenotype is maintained by Atoh1 in the cancer region of intraductal papillary mucinous neoplasm.
Cancer science - 1 Feb 2021
Katsukura Nobuhiro, Watanabe Sho, Shirasaki Tomoaki, Hibiya Shuji, Kano Yoshihito, Akahoshi Keiichi, Tanabe Minoru, Kirimura Susumu, Akashi Takumi, Kitagawa Masanobu, Okamoto Ryuichi, Watanabe Mamoru, Tsuchiya Kiichiro
Abstract excerpt
Intraductal papillary mucinous neoplasm (IPMN) is a precancerous lesion of pancreatic cancer. Although there are 4 types of IPMN, among which intestinal-type IPMN is likely to progress into invasive cancer known as colloid carcinoma, no information regarding the involvement of the intestinal phenotype in the carcinogenesis of IPMN exists. The present study was conducted to explore how the intestinal...
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