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The critical role of ZP genes in female infertility characterized by empty follicle syndrome and oocyte degeneration.

Fertility and sterility - 1 May 2021

Yang Ping, Chen Tailai, Liu Yuqing, Hou Zhenzhen, Wu Keliang, Cao Yongzhi, Zhang Jiangtao, Wang Zhao, Zhao Han

Abstract excerpt

OBJECTIVE: To identify the major causative gene(s) of genuine empty follicle syndrome (GEFS) characterized by oocyte degeneration. DESIGN: Genetic and functional studies. SETTING: University-based reproductive medicine center. PATIENT(S): Thirty-five unrelated women with GEFS and oocyte degeneration. INTERVENTION(S): Whole-exome sequencing (WES) and targeted Sanger sequencing. MAIN OUTCOME MEASURE(S): Variants...

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Source

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PMID: 33272616
DOI: 10.1016/j.fertnstert.2020.11.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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