Article
Correlation of Radiation Response of Cervical Cancer Stem Cells with Their Initial Number before Treatment and Molecular Genetic Features of Papillomavirus Infection.
Bulletin of experimental biology and medicine - 1 Dec 2020
Zamulaeva I A, Selivanova E I, Kiseleva V I, Matchuk O N, Krikunova L I, Mkrtchyan L S, Kaprin A D
Abstract excerpt
The proportion of CD44+CD24low cancer stem cells (CSC) was determined in cervical scrapings of 41 patients with squamous cell carcinoma of the uterine cervix before treatment and after irradiation in a total focal dose of 10 Gy. The relationship of quantitative changes in the CSC population with such parameters of papillomavirus infection as genotype, viral load, and physical status of HPV DNA (the absence or...
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