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Article

Trajectory of Unawareness of Memory Decline in Individuals With Autosomal Dominant Alzheimer Disease.

JAMA network open - 1 Dec 2020

Vannini Patrizia, Hanseeuw Bernard J, Gatchel Jennifer R, Sikkes Sietske A M, Alzate Diana, Zuluaga Yesica, Moreno Sonia, Mendez Luis, Baena Ana, Ospina-Lopera Paula, Tirado Victoria, Henao Eliana, Acosta-Baena Natalia, Giraldo Margarita, Lopera Francisco, Quiroz Yakeel T

Abstract excerpt

Importance: Recent studies have suggested that unawareness, or anosognosia, of memory decline is present in predementia stages of Alzheimer disease (AD) and may serve as an early symptomatic indicator of AD. Objective: To investigate the evolution of anosognosia of memory decline in individuals who carry the PSEN1 E280A variant for autosomal dominant AD compared with family members who do not carry the variant....

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Identifiers

PMID: 33263761
DOI: 10.1001/jamanetworkopen.2020.27472
PMCID: PMC7711319

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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