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Article

Self-reported memory complaints: implications from a longitudinal cohort with autopsies.

Neurology - 7 Oct 2014

Kryscio Richard J, Abner Erin L, Cooper Gregory E, Fardo David W, Jicha Gregory A, Nelson Peter T, Smith Charles D, Van Eldik Linda J, Wan Lijie, Schmitt Frederick A

Abstract excerpt

OBJECTIVE: We assessed salience of subjective memory complaints (SMCs) by older individuals as a predictor of subsequent cognitive impairment while accounting for risk factors and eventual neuropathologies. METHODS: Subjects (n = 531) enrolled while cognitively intact at the University of Kentucky were asked annually if they perceived changes in memory since their last visit. A multistate model estimated when...

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Identifiers

PMID: 25253756
DOI: 10.1212/WNL.0000000000000856
PMCID: PMC4189103

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APOE

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