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Article

Effect of D614G Spike Variant on Immunoglobulin G, M, or A Spike Seroassay Performance.

The Journal of infectious diseases - 3 Mar 2021

Klumpp-Thomas Carleen, Kalish Heather, Hicks Jennifer, Mehalko Jennifer, Drew Matthew, Memoli Matthew J, Hall Matthew D, Esposito Dominic, Sadtler Kaitlyn

Abstract excerpt

Emergence of a new spike protein variant (D614G) with increased infectivity has prompted many to analyze its role in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. There is concern regarding whether an individual exposed to one variant of a virus will have cross-reactive memory to the second variant. Accordingly, we analyzed the serologic reactivity of both variants, and we found that...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33257936
DOI: 10.1093/infdis/jiaa743
PMCID: PMC7798976

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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