Article
The effects of luteinising hormone gene polymorphism on the outcomes of in vitro fertilisation and embryo transfer.
Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology - 1 Oct 2021
Ku Yeonhee, Hong Min A, Chae Soo Jin, Lim Kyung Sil, Lee Won-Don, Lim Jin Ho, Choi Young Min
Abstract excerpt
Trp8Arg polymorphism of the LH beta gene has decreased bioactivity in vivo and previous studies showed conflicting data on the effect of LH beta gene polymorphism on the IVF outcome. In this study, 591 IVF patients were recruited. Patients with the variant allele(s) were the carrier group. In GnRH antagonist cycles, the clinical pregnancy rate was significantly lower in the carrier group (18.9%) than in the...
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