Article
BRCA gene testing in women with high-grade serous ovarian carcinoma.
Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology - 1 Aug 2021
Kansu Bengi, Gardner Jennifer, Price-Tate Rachel, Murch Oliver, Murray Alex
Abstract excerpt
The objective of this study was to compare the pick-up rate of pathogenic BRCA variants in those with a high-grade serous ovarian carcinoma (HGSOC) undergoing oncology-led testing with the traditional genetics family history-based testing model. With novel therapies, BRCA status can affect treatment. Welsh oncologists are now testing all women with HGSOC at diagnosis rather than referring to genetics, where...
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