Article
Biological Characteristics and Patterns of Codon Usage Evolution for the African Genotype Zika Virus.
Viruses - 14 Nov 2020
Faye Martin, Zein Naimah, Loucoubar Cheikh, Weidmann Manfred, Faye Ousmane, Cunha Marielton Dos Passos, Zanotto Paolo Marinho de Andrade, Alpha Sall Amadou, Faye Oumar
Abstract excerpt
We investigated temporal trends of codon usage changes for different host species to determine their importance in Zika virus (ZIKV) evolution. Viral spillover resulting from the potential of codon adaptation to host genome was also assessed for the African genotype ZIKV in comparison to the Asian genotype. To improve our understanding on its zoonotic maintenance, we evaluated in vitro the biological properties...
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