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Article

Codon adaptation biases among sylvatic and urban genotypes of Dengue virus type 2.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Oct 2018

Dos Passos Cunha Marielton, Ortiz-Baez Ayda Susana, de Melo Freire Caio César, de Andrade Zanotto Paolo Marinho

Abstract excerpt

Dengue virus (DENV) emerged from the sylvatic environment and colonized urban settings, being sustained in a human-Aedes-human transmission chain, mainly by the bites of females of the anthropophilic species Aedes aegypti. Herein, we sought evidence for fine-tuning in viral codon usage, possibly due to viral adaptation to human transmission. We compared the codon adaptation of DENV serotype 2 (DENV-2) genotypes...

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Identifiers

PMID: 29792991
DOI: 10.1016/j.meegid.2018.05.017
PMCID: PMC7106335

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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