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Article

Impaired Platelet Function in Sept8-Deficient Mice In Vitro.

Thrombosis and haemostasis - 1 Apr 2021

Neubauer Katharina, Jurk Kerstin, Petermann Victoria, Kumm Elena, Zieger Barbara

Abstract excerpt

Septins (Septs) are a widely expressed protein family of 13 mammalian members, recognized as a unique component of the cytoskeleton. In human platelets, we previously described that SEPT4 and SEPT8 are localized surrounding α-granules and move to the platelet surface after activation, indicating a possible role in platelet physiology. In this study, we investigated the impact of Sept8 on platelet function in...

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Identifiers

PMID: 33202444
DOI: 10.1055/s-0040-1718733

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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