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Article

Characterization of the plasma proteomic profile of frailty phenotype.

GeroScience - 1 Apr 2021

Landino Kristina, Tanaka Toshiko, Fantoni Giovanna, Candia Julián, Bandinelli Stefania, Ferrucci Luigi

Abstract excerpt

Frailty is a risk factor for poor health outcomes in older adults. The aim of this study was to identify plasma proteomic biomarkers of frailty in 752 men and women older than 65 years of age from the InCHIANTI study. One thousand three hundred one plasma proteins were measured using an aptamer-based assay. Associations of each protein with frailty status were assessed using logistic regression and four proteins...

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Identifiers

PMID: 33200349
DOI: 10.1007/s11357-020-00288-9
PMCID: PMC8110642

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