Article
Phenotypic variation of transcriptomic cell types in mouse motor cortex.
Nature - 1 Oct 2021
Scala Federico, Kobak Dmitry, Bernabucci Matteo, Bernaerts Yves, Cadwell Cathryn René, Castro Jesus Ramon, Hartmanis Leonard, Jiang Xiaolong, Laturnus Sophie, Miranda Elanine, Mulherkar Shalaka, Tan Zheng Huan, Yao Zizhen, Zeng Hongkui, Sandberg Rickard, Berens Philipp, Tolias Andreas S
Abstract excerpt
Cortical neurons exhibit extreme diversity in gene expression as well as in morphological and electrophysiological properties1,2. Most existing neural taxonomies are based on either transcriptomic3,4 or morpho-electric5,6 criteria, as it has been technically challenging to study both aspects of neuronal diversity in the same set of cells7. Here we used Patch-seq8 to combine patch-clamp recording, biocytin...
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