The Role of the BDNF Val66Met Polymorphism in Recovery of Aphasia After Stroke.

doi:10.1177/1545968317723752

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The Role of the BDNF Val66Met Polymorphism in Recovery of Aphasia After Stroke.

Neurorehabilitation and neural repair - 1 Sept 2017

de Boer Riemke G A, Spielmann Kerstin, Heijenbrok-Kal Majanka H, van der Vliet Rick, Ribbers Gerard M, van de Sandt-Koenderman W Mieke E

Abstract excerpt

BACKGROUND: Brain-derived neurotrophic factor (BDNF) is assumed to play a role in mediating neuroplasticity after stroke. Carriers of the function-limiting Val66Met (rs6265) single nucleotide polymorphism (SNP) may have a downregulation in BDNF secretion, which may lead to a poorer prognosis after stroke compared to noncarriers in motor learning and motor function recovery. The present study investigates whether...

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PMID: 28818006
DOI: 10.1177/1545968317723752

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