Article
Exploring the Role of Contactins across Psychological, Psychiatric and Cardiometabolic Traits within UK Biobank.
Genes - 10 Nov 2020
Morris Julia, Leung Soddy Sau Yu, Bailey Mark E S, Cullen Breda, Ferguson Amy, Graham Nicholas, Johnston Keira J A, Lyall Donald M, Lyall Laura M, Ward Joey, Smith Daniel J, Strawbridge Rona J
Abstract excerpt
Individuals with severe mental illness have an increased risk of cardiometabolic diseases compared to the general population. Shared risk factors and medication effects explain part of this excess risk; however, there is growing evidence to suggest that shared biology (including genetic variation) is likely to contribute to comorbidity between mental and physical illness. Contactins are a family of genes involved...
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